Genetics
HapMap 3 Points The Way Forward For Human Genetics Studies
New findings show the value of genetic studies across human populations and the value of the latest DNA sequencing technologies to interrogate genetic variation. The results, from the latest phase of the international HapMap Project, are reported in Nature...
Categories: Genetics
A Genetic Predisposition To Alcohol Dependence May Be Indicated By Sensitivity To Alcohol Odors
Single nucleotide polymorphisms (SNPs) are DNA sequence variations that occur when a single nucleotide in the genome sequence is altered. Prior research suggested an association between SNPs in a gene that encodes aspects of the brain's gamma-amino butyric acid (GABA)-A receptors (the GABRA2 gene) and alcohol dependence...
Categories: Genetics
Chromosomal Rearrangement, Gene Copy Number Methods Featured In Cold Spring Harbor Protocols
A cell devotes a significant amount of effort to maintaining the stability of its genome, preventing the sorts of chromosomal rearrangements characteristic of many cancers. Assays that measure the rate of gross chromosomal rearrangements (GCRs) are needed in order to understand the individual genes and the different pathways that suppress genomic instability...
Categories: Genetics
Novel Nanotechnology Collaboration Leads To Breakthrough In Cancer Research
One of the most difficult aspects of working at the nanoscale is actually seeing the object being worked on. Biological structures like viruses, which are smaller than the wavelength of light, are invisible to standard optical microscopes and difficult to capture in their native form with other imaging techniques...
Categories: Genetics
RNAi Screening Used For The First Time To Study Ewing's Sarcoma
The first study of Ewing's sarcoma that screened hundreds of genes based on how they affect cell growth has identified two potential anti-cancer drug targets, according to a scientific paper by the Translational Genomics Research Institute (TGen) published in the journal Molecular Cancer...
Categories: Genetics
Resistant Bacteria Protect The Colony
In the war against antibiotics, bacteria aren't selfish. According to a new report from Howard Hughes Medical Institute (HHMI) researchers, a handful of resistant pathogens can protect an entire colony...
Categories: Genetics
2-D Structure Of Thousands Of RNA Molecules Displayed On Stanford-Developed App
"There's an app for that." To a cadre of scientists, the familiar phrase will soon mean they can enter a specific RNA from baker's yeast into their iPhone and see a depiction of its two-dimensional structure - thanks to a new technology developed by scientists at Stanford University...
Categories: Genetics
Capacity For Exercise Can Be Inherited, Suggesting That Pharmaceutical Drugs Can Be Used To Alter Activity Levels In Humans
Biologists at the University of California, Riverside have found that voluntary activity, such as daily exercise, is a highly heritable trait that can be passed down genetically to successive generations. Working on mice in the lab, they found that activity level can be enhanced with "selective breeding"- the process of breeding plants and animals for particular genetic traits...
Categories: Genetics
Study: Preemptive Surgery May Help Prevent Cancer For Some Women
A study published in the Journal of the American Medical Association suggests that women with a gene mutation linked to breast and ovarian cancer face lower risks of developing such cancer after receiving mastectomies or having their ovaries removed, The Wall Street Journal reports...
Categories: Genetics
Breast Cancer Prognosis Prediction Tool: Microsoft Excel-Based Algorithm
Using readily available computer programs, researchers have developed a system to identify genes that will be useful in the classification of breast cancer. The algorithm, described in BioMed Central's open access Journal of Experimental & Clinical Cancer Research will enable researchers to quickly generate valuable gene signatures without specialized software or extensive bioinformatics training...
Categories: Genetics
DNA From National Psoriasis Victor Henschel BioBank Released For Study
Millions of Americans struggling with psoriasis and psoriatic arthritis are one step closer to a cure with the first-ever release of National Psoriasis Victor Henschel BioBank DNA samples for use in psoriasis research. The samples will allow scientists to uncover the unknowns about the genetics of psoriatic disease and its causes. James T. Elder, M.D., Ph.D...
Categories: Genetics
Microsoft Excel-based Algorithm Predicts Cancer Prognosis
Using readily available computer programs, researchers have developed a system to identify genes that will be useful in the classification of breast cancer. The algorithm, described in BioMed Central's open access Journal of Experimental & Clinical Cancer Research will enable researchers to quickly generate valuable gene signatures without specialized software or extensive bioinformatics training...
Categories: Genetics
Nanobiotechnology To Fight Cancer And Other Illnesses
Two new groundbreaking scientific papers by researchers at UC Santa Barbara demonstrate the synthesis of nanosize biological particles with the potential to fight cancer and other illnesses. The studies introduce new approaches that are considered "green" nanobiotechnology because they use no artificial compounds...
Categories: Genetics
Group Health Study Reveals That People Want To Be Asked Before Sharing Genetic Data
People want to be informed and asked for consent before deciding whether to let researchers share their genetic information in a federal database. This is according to a team of investigators at Group Health Research Institute and the University of Washington (UW). The team's report, called "Glad You Asked," is in the September 2010 Journal of Empirical Research on Human Research Ethics...
Categories: Genetics
Data From Mipomersen Phase 3 Trial In heFH Patients Presented At ESC
Genzyme Corp. (NASDAQ: GENZ) and Isis Pharmaceuticals Inc. (NASDAQ: ISIS) announced that data from the phase 3 study of mipomersen in patients with heterozygous familial hypercholesterolemia (heFH) were presented at the European Society of Cardiology's Congress 2010 in Stockholm, Sweden...
Categories: Genetics
Discovery Of New Protein That Gets To The Roots Of Obesity And Osteoporosis
Here's good news for anyone trying to lose weight or has osteoporosis: Scientists from Maine are on the trail of a weight loss drug that may revolutionize how we treat these two conditions...
Categories: Genetics
Physically Active Lifestyle May Reduce Genetic Predisposition To Obesity
New research from the UK suggests that living an active lifestyle can reduce people's genetic predisposition to obesity by about 40 per cent, challenging a popular view that exercise doesn't help people lose weight if they are genetically predisposed to obesity...
Categories: Genetics
Genetic Variation In Key Cell Pumping Mechanism Reduces Clopidogrel Treatment Effects, Leaving Those Affected At Increased Cardiovascular Event Risk
A study published Online First and in an upcoming Lancet shows that patients with a genetic variation affecting a key protein pump in drug transport do not respond as well to the anticlotting drug clopidogrel-as such, patients with this variation at are at increased risk of cardiovascular events with standard clopidogrel treatment...
Categories: Genetics
Anti-Cancer Gene To Be Activated By Researchers
Researchers at the Faculty of Health Sciences have succeeded in decoding the genetic key that gives particular intestinal cells their identity. With this knowledge of the complex network of genes the researchers now hope to stop colon cancer by activating special anti-cancer genes. Colon sloughs lining The intestines have to work properly if we are to benefit from the food we eat...
Categories: Genetics
Researchers Develop Hybrid Protein Tools For Gene Cutting And Editing
An Iowa State University team of researchers has developed a type of hybrid proteins that can make double-strand DNA breaks at specific sites in living cells, possibly leading to better gene replacement and gene editing therapies...
Categories: Genetics
- Yogurt cures AIDS? Probiotics study by AHF
- Remember PCP and KS ?
- Coming of Age in the Era of AIDS
- Forcing pregnant women to take HIV tests
- Delusions in HIV and cancer treatment
- Competing theories of AIDS: Is HIV irrelevant?
- Causes of death among children younger than 4
- Syphilis causes "HIV" viral load spike, and T-cell decrease
- Eating E numbers: What is behind them? - Health Supreme NewsGrabs Tuesday, 31 August 2010
- EU food-supplement directive to override consumer choice - Health Supreme NewsGrabs Tuesday, 24 August 2010
- Appeals Court Stays Proposition 8 Injunction
- WHO Says Swine Flu Pandemic Over - Health Supreme NewsGrabs Sunday, 15 August 2010
- A Flipping Point on Gay Marriage?
- Reason Morning Links: Parking Prices, a Border Bill, and the Big Baby Conspiracy
- Is It Crazy to Call Californians Irrational?
- Gary Johnson Distances Himself From Libertarianism
- Overreaching on Gay Marriage
- Characterization of vascular strain during in-vitro angioplasty with high-resolution ultrasound speckle tracking
- Dynamic models of immune responses: what is the ideal level of detail?
- Serotonin synthesis, release and reuptake in terminals: a mathematical model
- A novel approach to modelling water transport and drug diffusion through the stratum corneum
- Network, degeneracy and bow tie Integrating paradigms and architectures to grasp the complexity of the immune system
- Money from Bill and Melinda Gates will help beat Dengue fever in Australia
- Australian scientists win funds for new research
- South Carolina health coverage, cigarette tax bill stalls in state Senate
- Supporters, opponents of comparative effectiveness research 'gearing up' to clash over planned efforts, New York Times reports
- Survey examines wait times for appointments with specialists in 15 U.S. cities
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- HIV Surveillance Supplemental Report, Volume 15, Number 1
- e-HAP Pubs August 17, 2010
- Poster: Communities in Crisis: Is There a Generalized HIV Epidemic in Impoverished Urban Areas of the United States?
- Factsheet: Projecting Possible Future Courses of the HIV Epidemic in the United States
- e-HAP FYI August 9, 2010
- Effect of Rifampicin on Efavirenz Pharmacokinetics in HIV-Infected Children With Tuberculosis.
- Phenotypic and Functional Characterization of HIV-1-Specific CD4+CD8+ Double-Positive T Cells in Early and Chronic HIV-1 Infection.
- Hepatitis C Virus Coinfection Does Not Influence the CD4 Cell Recovery in HIV-1-Infected Patients With Maximum Virologic Suppression.
- Nonalcoholic Fatty Liver Disease Among HIV-Infected Persons.
- A Once-Daily Lopinavir/Ritonavir-Based Regimen Is Noninferior to Twice-Daily Dosing and Results in Similar Safety and Tolerability in Antiretroviral-Naive Subjects Through 48 Weeks.
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